Pohang Accelerator Laboratory, POSTECH

- 2008. 3. – 2012. 3. : Ph.D. in Chemistry, Chonnam National University, South Korea

- 2006. 3. – 2008. 2. : M.S. in Chemistry, Chonnam National University, South Korea

- 1998. 3. – 2006. 2. : B.S. in Chemistry, Chonnam National University, South Korea

- 2023-present: Collaborator, MX3, Australian Synchrotron, ANSTO, Australia

- 2015-present: Beamline Scientist, Pohang Accelerator Laboratory (PAL), POSTECH, South Korea

- 2013-2015: Postdoctoral Fellow, National Cancer Institute, NIH, USA.

1. Seo PW, Hofmann A, Kim JH, et al. Structural features of a minimal intact methyltransferase of a type I restriction-modification system. Int J Biol Macromol. 2022;208:381-389. (Corresponding author)

2. Gu DH, Eo C, Hwangbo SA, et al. BL-11C Micro-MX: a high-flux microfocus macromolecular-crystallography beamline for micrometre-sized protein crystals at Pohang Light Source II. J Synchrotron Radiat. 2021;28(Pt 4):1210-1215. (Corresponding author)

3. Gu D, Eo C, Jeong DT, Kim J, Park SY. Synchrotron serial crystallography at 11C beamline of Pohang Light Source-II. Biodesign. 2020; 8(4) 93-98. (Corresponding author)

4. Park SY, Choi H, Eo C, Cho Y, Nam KH. Fixed-Target Serial Synchrotron Crystallography Using Nylon Mesh and Enclosed Film-Based Sample Holder. Crystals. 2020; 10(9):803. (First author)

5. Kim H, Kubori T, Yamazaki K, et al. Structural basis for effector protein recognition by the Dot/Icm Type IVB coupling protein complex. Nat Commun. 2020;11(1):2623. (Shared author)

6. Park SY, Kim JS. A short guide to histone deacetylases including recent progress on class II enzymes. Exp Mol Med. 2020;52(2):204-212. (First author)

7. Hwangbo SA, Kim JW, Jung SJ, et al. Characterization of a Dimeric Arginase From Zymomonas mobilis ZM4. Front Microbiol. 2019;10:2755. (Corresponding author

8. Park SY, Nam KH. Sample delivery using viscous media, a syringe and a syringe pump for serial crystallography. J Synchrotron Radiat. 2019;26(Pt 5):1815-1819. (Corresponding author)

9. Park SY, Kim GS, Hwang HJ, et al. Structural basis of the specific interaction of SMRT corepressor with histone deacetylase 4. Nucleic Acids Res. 2018;46(22):11776-11788. (Corresponding author)

10. Cross M, Biberacher S, Park SY, et al. Trehalose 6-phosphate phosphatases of Pseudomonas aeruginosa. FASEB J. 2018;32(10):5470-5482. (Co-first author)

Protein structural study and beamline science

My major is structural biology based on protein crystallography. After joining the PAL, I have carried out the 11C Micro-MX beamline, serial crystallography system constructions and development of a microfluidics chip for protein dynamics observation. In parallel, I have proceeded structural studies on proteins relating to type I restriction-modification system in bacterial defense, histone deacetylase, human centrosome kinase Plk4 complex and key enzymes of the fermentative pathway in ethanol-producing bacteria.