College of Pharmacy, Chosun University

- 2004. 3 – 2008. 8.: Ph.D. in Physical Chemistry, Department of Chemistry, Pusan National University, South Korea.

- 2002. 3. – 2004. 2.: M.S. in Physical Chemistry, Department of Chemistry, Pusan National University, South Korea.

- 1997. 3. – 2002. 2.: Bachelor in Natural Science (major: Chemisty), Department of Chemistry, Pusan National University, Korea.

- 2019-2020: Director, Pharmaceutical Research Institute in Chosun University

- 2012-2014: Chairperson, College of Pharmacy, Chosun University

- 2011-present: Member, The Korean Chemical Society

- 2011-present: Member, The Pharmaceutical society of Korea

- 2019-present: Member, Korean Institute of Intellligent Systems

1. Liu Z, et al. 2023. Macrosphelides from Antarctic fungus Pseudogymnoascus sp. (strain SF-7351) and their neuroprotective effects on BV2 and HT22 cells. Chemico-Biological Interactions 385:110718. (IF=5.1)

2. Chen Z, et al. 2023. Discovery of PMSA Derivative 11 as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis In Vitro and In Vivo J. Med. Chem. 66:6766-6781 (IF: 8.04)

3. Kim H, et al. 2023. Computational Probing of the Folding Mechanism of Human Telomeric G‑Quadruplex DNA J. Chem. Inf. Model. 3c0127 (IF: 5.6)

4. Lim J, et al. 2022. Synthesis of DPIE [2-(1,2-Diphenyl-1H-indol-3-yl)ethanamine] Derivatives and Their Regulatory Effects on Pro-Inflammatory Cytokine Production in IL-1β-Stimulated Primary Human Oral Cells. Molecules 27:899 (IF: 4.6)

5. Bae JA, et al. 2021. A new KSRP-binding compound suppresses distant metastasis of colorectal cancer by targeting the oncogenic KITENIN complex.

6. Molecular Cancer 20:78 (IF: 37.3) Park JY, et al. 2021. A missense variant in SHARPIN mediates Alzheimer’s disease-specific brain damages Translational Psychiatry 11:590 (IF:6.8)

Computational chemistry and Medicinal chemistry:

My major interest is to study the mechanism of action of macromolecules (GPCR receptor, enzymes, nucleic acid, etc.) and protein-protein interactions. In addition, in drug discovery, I am interested in drug-target protein interaction and structure-based structure-activity relationship (SAR) and my computational skills are used for docking simulation of target-ligand, molecular modeling, virtual screening using databases, de novo design, lead optimization and prediction of ADMET.